What symptoms are expected following an overdose of oxycodone (Percocet)?

Oxycodone, a powerful opioid analgesic, affects the central nervous system and can lead to specific symptoms when an overdose occurs. The correct symptoms include hypotension (low blood pressure), hypoventilation (decreased breathing rate), and pinpoint pupils (miosis).

Hypotension can occur because opioids depress the autonomic nervous system, leading to reduced cardiac output and vascular resistance. Hypoventilation is another critical effect; opioids suppress the respiratory drive, resulting in shallow or ineffective breathing rates, which can lead to respiratory failure. The presence of pinpoint pupils is a hallmark sign of opioid intoxication or overdose, as opioids interact with receptors in the brain that regulate pupil size.

Understanding these signs is vital for emergency medical responders because they indicate a potentially life-threatening situation requiring immediate intervention, such as airway management and the administration of naloxone, an opioid antagonist. Recognizing these symptoms can guide proper treatment and ensure the safety of the patient.